Flygut: an atlas of the Drosophila adult midgut

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Gene name Alas
Flybase description The gene Aminolevulinate synthase is referred to in FlyBase by the symbol Dmel\Alas (CG3017, FBgn0020764).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 2.7865 3.755 2.778561 1.3315 0.596548 0.5736 1.9666 1.945994
    Affimetrix absolute value 9.847 9.492 9.632 8.796 9.066 8.853 9.514 9.19
    Affymetric present call in "x" number of chips 3 3 3 3 3 3 3 3
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
Based on sequence similarity, it is predicted to have molecular function: 5-aminolevulinate synthase activity.
Based on sequence similarity, it is predicted to be involved in the biological process: heme biosynthetic process.
3 alleles are reported.
No phenotypic data is available.
It has one annotated transcript and one annotated polypeptide.
Protein features are: Aminotransferase, class I/classII; Pyridoxal phosphate-dependent transferase, major domain; Pyridoxal phosphate-dependent transferase, major region, subdomain 1; Pyridoxal phosphate-dependent transferase, major region, subdomain 2; Tetrapyrrole biosynthesis, 5-aminolevulinic acid synthase.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of moderate expression.
Peak expression observed in adult male stages.
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