Flygut: an atlas of the Drosophila adult midgut

 Mouche Logo lab lemaitre Bbcf logo
Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
Search expression data by gene:
Gene name Sodh-2
Flybase description The gene Sorbitol dehydrogenase-2 is referred to in FlyBase by the symbol Dmel\Sodh-2 (CG4649, FBgn0022359).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -4.0736 -10.3573 -20.726189 -35.2637 -37.568247 -43.783 -7.39209 -19.738139
    Affimetrix absolute value 6.64 4.264 3.813 3.255 3.542 3.113 5.74 3.941
    Affymetric present call in "x" number of chips 3 2 0 0 0 0 3 0
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
Based on sequence similarity, it is predicted to have molecular function: L-iditol 2-dehydrogenase activity.
An electronic pipeline based on InterPro domains suggests that it is involved in the biological process: oxidation-reduction process.
6 alleles are reported.
No phenotypic data is available.
It has one annotated transcript and one annotated polypeptide.
Protein features are: Alcohol dehydrogenase GroES-like; Alcohol dehydrogenase superfamily, zinc-type; Alcohol dehydrogenase, C-terminal; Alcohol dehydrogenase, zinc-type, conserved site; GroES-like; NAD(P)-binding domain.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of moderate expression.
Peak expression observed at stages throughout the larval period.
.