Flygut: an atlas of the Drosophila adult midgut

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Gene name Pka-R2
Flybase description The gene cAMP-dependent protein kinase R2 is referred to in FlyBase by the symbol Dmel\Pka-R2 (CG15862, FBgn0022382).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -2.1549 -2.5209 -2.30245 -1.7994 -3.130856 -2.4575 -2.728 -3.121224
    Affimetrix absolute value 7.358 6.288 7.004 7.559 7.13 7.269 7.108 6.632
    Affymetric present call in "x" number of chips 3 3 3 3 3 3 3 3
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
There is experimental evidence that it has the molecular function: protein binding.
There is experimental evidence that it is involved in the biological process: axon guidance; circadian rhythm; locomotor rhythm; behavioral response to ethanol; behavioral response to cocaine.
24 alleles are reported.
The phenotypes of these alleles are annotated with 13 unique terms, many of which group under: organ system; organ system subdivision; adult segment; thoracic segment; peripheral nervous system; multicellular structure; non-connected developing system; portion of tissue; eo support cell; external compound sense organ.
It has 5 annotated transcripts and 5 annotated polypeptides.
Protein features are: Cyclic nucleotide-binding domain; Cyclic nucleotide-binding, conserved site; Cyclic nucleotide-binding-like; RmlC-like jelly roll fold; cAMP-dependent protein kinase regulatory subunit; cAMP-dependent protein kinase, regulatory subunit, type I/II alpha/beta; cAMP/cGMP-dependent protein kinase.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of very low expression.
Peak expression observed during late pupal stages.
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