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Gene name | Hel89B | ||||||||||||||||||||||||||||||||||||
Flybase description | The gene Helicase 89B is referred to in FlyBase by the symbol Dmel\Hel89B (CG4261, FBgn0022787). | ||||||||||||||||||||||||||||||||||||
Expression data along the gut |
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Intestinal gene expression in different physiological conditions |
Ecc15: flies orally infected with Erwinia carotovora carotovora 15. Pe: flies orally infected with Pseudomonas entomophila. Pe gacA: flies orally infecte with Pseudomonas entomophila gacA. For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe. |
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Gene details (from Flybase) | It is a protein_coding_gene from Drosophila melanogaster. Based on sequence similarity, it is predicted to have molecular function: ATP-dependent DNA helicase activity. There is experimental evidence that it is involved in the biological process: innate immune response; Toll signaling pathway; defense response to bacterium; positive regulation of antibacterial peptide biosynthetic process; antimicrobial humoral response. 17 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. Protein features are: Armadillo-like helical; Armadillo-type fold; DEAD-like helicase; Domain of unknown function DUF3535; Helicase, C-terminal; SNF2-related. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of moderate expression. Peak expression observed within 00-18 hour embryonic stages, during late larval stages, at stages throughout the pupal period. . |