Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
Search expression data by gene:
Gene name melt
Flybase description The gene melted is referred to in FlyBase by the symbol Dmel\melt (CG8624, FBgn0023001).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -18.6643 -5.5893 -13.262094 -9.8773 -10.956369 -9.3398 -19.44913 -11.467562
    Affimetrix absolute value 4.189 5.136 4.449 5.126 5.311 5.34 4.278 4.762
    Affymetric present call in "x" number of chips 0 3 1 3 2 3 1 1
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
There is experimental evidence that it has the molecular function: phosphatidylinositol binding; phosphatidylinositol-5-phosphate binding.
There is experimental evidence that it is involved in the biological process: insulin receptor signaling pathway; ectoderm development; sequestering of triglyceride; R8 cell fate specification; peripheral nervous system development.
17 alleles are reported.
The phenotypes of these alleles are annotated with: photoreceptor cell R8 of yellow ommatidium; presumptive embryonic/larval peripheral nervous system; presumptive embryonic/larval nervous system; wing.
It has 2 annotated transcripts and 2 annotated polypeptides.
Protein features are: Armadillo-like helical; Armadillo-type fold; Pleckstrin homology domain; Pleckstrin homology-type.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of very low expression.
Peak expression observed at stages throughout the pupal period.
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