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| Gene name | Clk | ||||||||||||||||||||||||||||||||||||
| Flybase description | The gene Clock is referred to in FlyBase by the symbol Dmel\Clk (CG7391, FBgn0023076). | ||||||||||||||||||||||||||||||||||||
| Expression data along the gut |
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| Intestinal gene expression in different physiological conditions |
Ecc15: flies orally infected with Erwinia carotovora carotovora 15. Pe: flies orally infected with Pseudomonas entomophila. Pe gacA: flies orally infecte with Pseudomonas entomophila gacA. For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe. |
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| Gene details (from Flybase) | It is a protein_coding_gene from Drosophila melanogaster. There is experimental evidence that it has the molecular function: protein binding; protein heterodimerization activity; DNA binding. There is experimental evidence that it is involved in the biological process: regulation of circadian sleep/wake cycle, sleep; circadian rhythm; locomotor rhythm; positive regulation of transcription, DNA-dependent; circadian regulation of gene expression. 27 alleles are reported. The phenotype of these alleles is annotated with: larval LN period neuron. It has 3 annotated transcripts and 3 annotated polypeptides. Protein features are: Helix-loop-helix DNA-binding; Helix-loop-helix DNA-binding domain; Nuclear translocator; PAC motif; PAS; PAS fold-3. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of no expression detected. Peak expression observed in adult male stages. . |
