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Gene name | SNF1A | ||||||||||||||||||||||||||||||||||||
Flybase description | The gene SNF1A/AMP-activated protein kinase is referred to in FlyBase by the symbol Dmel\SNF1A (CG3051, FBgn0023169). | ||||||||||||||||||||||||||||||||||||
Expression data along the gut |
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Intestinal gene expression in different physiological conditions |
Ecc15: flies orally infected with Erwinia carotovora carotovora 15. Pe: flies orally infected with Pseudomonas entomophila. Pe gacA: flies orally infecte with Pseudomonas entomophila gacA. For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe. |
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Gene details (from Flybase) | It is a protein_coding_gene from Drosophila melanogaster. There is experimental evidence that it has the molecular function: AMP-activated protein kinase activity. There is experimental evidence that it is involved in the biological process: mitotic cell cycle; regulation of cell growth; protein phosphorylation; establishment or maintenance of epithelial cell apical/basal polarity; regulation of digestive system process; phagocytosis, engulfment. 28 alleles are reported. The phenotypes of these alleles are annotated with: embryonic/larval midgut; circular visceral muscle fiber; midgut muscle; hindgut muscle; embryonic/larval digestive system; embryonic/larval fat body; hindgut visceral muscle fiber; sensory neuron; longitudinal visceral muscle fiber. It has 3 annotated transcripts and 3 annotated polypeptides. Protein features are: Protein kinase, ATP binding site; Protein kinase, catalytic domain; Protein kinase-like domain; Serine/threonine-protein kinase domain; Serine/threonine-protein kinase, active site; Serine/threonine-protein kinase-like domain. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of moderately high expression. Peak expression observed at stages throughout embryogenesis, in stages of adults of both sexes. . |