Flygut: an atlas of the Drosophila adult midgut

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Gene name RhoGEF2
Flybase description The gene RhoGEF2 is referred to in FlyBase by the symbol Dmel\RhoGEF2 (CG9635, FBgn0023172).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -1.7606 0.4991 -2.107733 -0.3715 -3.466598 -1.1237 -0.42293 -2.904784
    Affimetrix absolute value 7.603 7.814 7.154 8.339 7.075 8.394 8.446 6.864
    Affymetric present call in "x" number of chips 3 3 3 3 3 3 3 3
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
Based on sequence similarity, it is predicted to have molecular function: diacylglycerol binding; Rho guanyl-nucleotide exchange factor activity.
There is experimental evidence for 15 unique biological process terms, many of which group under: cellular component organization or biogenesis; biological regulation; morphogenesis of embryonic epithelium; anatomical structure formation involved in morphogenesis; regulation of developmental process; multicellular organismal development; actin filament-based process; gastrulation; regulation of cell morphogenesis; pole cell development; morphogenesis of an epithelial fold; organelle organization; embryonic development via the syncytial blastoderm; open tracheal system development.
42 alleles are reported.
The phenotypes of these alleles are annotated with: presumptive embryonic salivary gland; wing disc; epithelial cell; posterior spiracle primordium; wing; mesoderm anlage; ventral midline.
It has 4 annotated transcripts and 4 annotated polypeptides.
Protein features are: Dbl homology (DH) domain; PDZ/DHR/GLGF; Pleckstrin homology domain; Pleckstrin homology-type; Protein kinase C-like, phorbol ester/diacylglycerol binding; Regulator of G protein signalling superfamily; Regulator of G protein signalling-like fold; Rho GTP exchange factor.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of moderate expression.
Peak expression observed at stages throughout embryogenesis, during late larval stages, at stages throughout the pupal period, in adult female stages.
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