Flygut: an atlas of the Drosophila adult midgut

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Gene name Parg
Flybase description The gene Poly(ADP-ribose) glycohydrolase is referred to in FlyBase by the symbol Dmel\Parg (CG2864, FBgn0023216).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -19.5178 -13.0491 -18.505204 -18.5372 -21.361317 -14.9762 -27.61594 -20.517612
    Affimetrix absolute value 4.136 3.938 3.971 4.185 4.355 4.664 3.787 3.928
    Affymetric present call in "x" number of chips 1 2 1 3 3 3 1 2
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
There is experimental evidence that it has the molecular function: poly(ADP-ribose) glycohydrolase activity.
There is experimental evidence that it is involved in the biological process: response to heat; regulation of histone acetylation; maintenance of protein location in nucleus; chromatin silencing; regulation of RNA splicing; carbohydrate metabolic process; phagocytosis, engulfment.
12 alleles are reported.
The phenotypes of these alleles are annotated with: nucleolus; dorsocentral bristle; mesothoracic leg; wing.
It has 2 annotated transcripts and 2 annotated polypeptides.
Protein features are: Poly(ADP-ribose) glycohydrolase.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of low expression.
Peak expression observed within 00-06 hour embryonic stages.
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