Flygut: an atlas of the Drosophila adult midgut

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Gene name Ac78C
Flybase description The gene Adenylyl cyclase 78C is referred to in FlyBase by the symbol Dmel\Ac78C (CG10564, FBgn0024150).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -2.3315 -6.7578 -29.519538 -39.2326 -62.735089 -19.4641 -3.56141 -33.438315
    Affimetrix absolute value 7.188 4.896 3.304 3.106 2.813 4.282 6.792 3.24
    Affymetric present call in "x" number of chips 3 3 0 1 0 3 3 2
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
Based on sequence similarity, it is predicted to have molecular function: adenylate cyclase activity.
There is experimental evidence that it is involved in the biological process: response to sucrose stimulus; response to trehalose stimulus; detection of chemical stimulus involved in sensory perception of sweet taste.
4 alleles are reported.
No phenotypic data is available.
It has 2 annotated transcripts and 2 annotated polypeptides.
Protein features are: Adenylate cyclase-like; Adenylyl cyclase class-3/4/guanylyl cyclase; Adenylyl cyclase class-3/4/guanylyl cyclase, conserved site.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of very low expression.
Peak expression observed within 00-06 hour embryonic stages.
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