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Gene name | gbb | ||||||||||||||||||||||||||||||||||||
Flybase description | The gene glass bottom boat is referred to in FlyBase by the symbol Dmel\gbb (CG5562, FBgn0024234). | ||||||||||||||||||||||||||||||||||||
Expression data along the gut |
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Intestinal gene expression in different physiological conditions |
Ecc15: flies orally infected with Erwinia carotovora carotovora 15. Pe: flies orally infected with Pseudomonas entomophila. Pe gacA: flies orally infecte with Pseudomonas entomophila gacA. For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe. |
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Gene details (from Flybase) | It is a protein_coding_gene from Drosophila melanogaster. Based on sequence similarity, it is predicted to have molecular function: transforming growth factor beta receptor binding. There is experimental evidence that it is involved in the biological process: neuromuscular synaptic transmission; regulation of neurotransmitter secretion; positive regulation of muscle organ development; ovarian follicle cell development; imaginal disc-derived wing vein morphogenesis; imaginal disc-derived wing vein specification; neuromuscular junction development; wing disc pattern formation. 27 alleles are reported. The phenotypes of these alleles are annotated with 47 unique terms, many of which group under: adult segment; organ system subdivision; organ system; thoracic segment; synapse; external compound sense organ; imaginal precursor; integumentary plate; integumentary specialisation; peripheral nervous system. It has one annotated transcript and one annotated polypeptide. Protein features are: Transforming growth factor beta, conserved site; Transforming growth factor-beta, C-terminal; Transforming growth factor-beta, N-terminal; Transforming growth factor-beta-related. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of moderate expression. Peak expression observed within 00-12 hour embryonic stages. . |