Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
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Gene name dnt
Flybase description The gene doughnut on 2 is referred to in FlyBase by the symbol Dmel\dnt (CG17559, FBgn0024245).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -10.5103 -12.6223 -20.174871 -16.4406 -26.393661 -24.0022 -23.70183 -20.521859
    Affimetrix absolute value 5.026 3.995 3.894 4.359 4.043 3.986 4.029 3.904
    Affymetric present call in "x" number of chips 3 2 1 2 1 1 0 0
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
There is experimental evidence that it has the molecular function: transmembrane receptor protein tyrosine kinase activity.
There is experimental evidence that it is involved in the biological process: axon guidance; lateral inhibition; signal transduction; muscle attachment; salivary gland morphogenesis.
11 alleles are reported.
The phenotypes of these alleles are annotated with: presumptive embryonic salivary gland; trichogen cell; mesothoracic tergum.
It has one annotated transcript and one annotated polypeptide.
Protein features are: Protein kinase, catalytic domain; Protein kinase-like domain; Serine-threonine/tyrosine-protein kinase; Tyrosine-protein kinase, active site; Tyrosine-protein kinase, catalytic domain; WIF domain.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of very low expression.
Peak expression observed within 00-06 hour embryonic stages.
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