Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
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Gene name WASp
Flybase description The gene WASp is referred to in FlyBase by the symbol Dmel\WASp (CG1520, FBgn0024273).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -12.4433 -1.8777 -1.799968 -1.5191 -3.35163 -2.6421 -10.84012 -2.585376
    Affimetrix absolute value 4.79 6.723 7.34 7.804 7.046 7.189 5.143 6.896
    Affymetric present call in "x" number of chips 0 3 3 3 3 3 2 3
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
There is experimental evidence that it has the molecular function: protein binding.
There is experimental evidence for 16 unique biological process terms, many of which group under: cellular component organization or biogenesis; biological regulation; system development; multicellular organismal development; regulation of developmental process; sensory organ development; regulation of cellular component organization; neuron differentiation; synaptic transmission; neuron projection development.
30 alleles are reported.
The phenotypes of these alleles are annotated with 22 unique terms, many of which group under: organ system; organ system subdivision; adult segment; sense organ; eo support cell; multicellular structure; integumentary plate; cell part; non-connected developing system; synapse; external compound sense organ; portion of tissue.
It has 3 annotated transcripts and 3 annotated polypeptides.
Protein features are: Actin-binding WH2; EVH1; PAK-box/P21-Rho-binding; Pleckstrin homology-type; Wiscott-Aldrich syndrome, C-terminal.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of moderate expression.
Peak expression observed within 00-06 and 12-24 hour embryonic stages, at stages throughout the larval period, at stages throughout the pupal period, in stages of adults of both sexes.
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