Flygut: an atlas of the Drosophila adult midgut

 Mouche Logo lab lemaitre Bbcf logo
Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
Search expression data by gene:
Gene name trio
Flybase description The gene trio is referred to in FlyBase by the symbol Dmel\trio (CG18214, FBgn0024277).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -30.4505 -9.5026 -17.749317 -16.2707 -27.563064 -19.7097 -36.36273 -19.557948
    Affimetrix absolute value 3.481 4.374 4.068 4.391 4.026 4.28 3.383 3.988
    Affymetric present call in "x" number of chips 0 3 2 2 2 2 0 2
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
There is experimental evidence that it has the molecular function: Rho guanyl-nucleotide exchange factor activity.
There is experimental evidence that it is involved in the biological process: central nervous system development; regulation of axonogenesis; Rho protein signal transduction; actin cytoskeleton organization; axon guidance; lateral inhibition; axon extension involved in development; mushroom body development; axon target recognition; peripheral nervous system development.
81 alleles are reported.
The phenotypes of these alleles are annotated with 25 unique terms, many of which group under: organ system subdivision; organ system; peripheral nervous system; adult segment; external compound sense organ; eo support cell; FBbt:00003689; FBbt:00003692; embryonic/larval neuron; non-connected developing system.
It has 6 annotated transcripts and 6 annotated polypeptides.
Protein features are: Cellular retinaldehyde-binding/triple function, C-terminal; Dbl homology (DH) domain; Guanine-nucleotide dissociation stimulator, CDC24, conserved site; Pleckstrin homology domain; Pleckstrin homology-type; Spectrin repeat; Spectrin/alpha-actinin; Src homology-3 domain.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of moderate expression.
Peak expression observed at stages throughout embryogenesis, at stages throughout the pupal period.
.