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| Gene name | Npc1a | ||||||||||||||||||||||||||||||||||||
| Flybase description | The gene Niemann-Pick type C-1a is referred to in FlyBase by the symbol Dmel\Npc1a (CG5722, FBgn0024320). | ||||||||||||||||||||||||||||||||||||
| Expression data along the gut |
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| Intestinal gene expression in different physiological conditions | There is not condition-dependent expression data available for this gene. | ||||||||||||||||||||||||||||||||||||
| Gene details (from Flybase) | It is a protein_coding_gene from Drosophila melanogaster. An electronic pipeline based on InterPro domains suggests that it has the molecular function: hedgehog receptor activity. There is experimental evidence that it is involved in the biological process: sperm individualization; sterol metabolic process; ecdysteroid biosynthetic process; molting cycle, chitin-based cuticle; regulation of cholesterol transport. 22 alleles are reported. The phenotypes of these alleles are annotated with: sperm individualization complex; individualization stage spermatid; seminal vesicle. It has 4 annotated transcripts and 4 annotated polypeptides. Protein features are: Niemann-Pick C type protein; Patched; Sterol-sensing domain. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of moderate expression. Peak expression observed during late larval stages, during early pupal stages. . |
