Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
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Gene name p38b
Flybase description The gene p38b is referred to in FlyBase by the symbol Dmel\p38b (CG7393, FBgn0024846).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 1.594 1.7731 1.877358 1.952 1.533763 1.2992 1.20616 1.650419
    Affimetrix absolute value 9.078 8.443 9.084 9.348 9.372 8.933 8.814 8.943
    Affymetric present call in "x" number of chips 3 3 3 3 3 3 3 3
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
There is experimental evidence that it has the molecular function: protein serine/threonine kinase activity.
There is experimental evidence for 19 unique biological process terms, many of which group under: biological regulation; response to stress; response to stimulus; cellular process; immune response; cellular component organization or biogenesis; cellular response to metal ion; response to nutrient levels; cellular response to arsenic-containing substance; response to hydrogen peroxide; post-embryonic organ morphogenesis; defense response to bacterium; defense response to fungus.
15 alleles are reported.
The phenotypes of these alleles are annotated with: wing; wing vein.
It has one annotated transcript and one annotated polypeptide.
Protein features are: MAP kinase, conserved site; MAP kinase, p38; Protein kinase, ATP binding site; Protein kinase, catalytic domain; Protein kinase-like domain; Serine/threonine-protein kinase domain; Serine/threonine-protein kinase-like domain.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of moderate expression.
Peak expression observed at stages throughout embryogenesis, at stages throughout the larval period, during early pupal stages, in stages of adults of both sexes.
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