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Gene name | agt | ||||||||||||||||||||||||||||||||||||
Flybase description | The gene O-6-alkylguanine-DNA alkyltransferase is referred to in FlyBase by the symbol Dmel\agt (CG1303, FBgn0024912). | ||||||||||||||||||||||||||||||||||||
Expression data along the gut |
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Intestinal gene expression in different physiological conditions |
Ecc15: flies orally infected with Erwinia carotovora carotovora 15. Pe: flies orally infected with Pseudomonas entomophila. Pe gacA: flies orally infecte with Pseudomonas entomophila gacA. For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe. |
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Gene details (from Flybase) | It is a protein_coding_gene from Drosophila melanogaster. There is experimental evidence that it has the molecular function: methylated-DNA-[protein]-cysteine S-methyltransferase activity. There is experimental evidence that it is involved in the biological process: DNA dealkylation involved in DNA repair. 3 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. Protein features are: Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding; Methylated-DNA-[protein]-cysteine S-methyltransferase, active site; Winged helix-turn-helix transcription repressor DNA-binding. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderate expression to a trough of very low expression. Peak expression observed within 00-06 hour embryonic stages, in stages of adults of both sexes. . |