Flygut: an atlas of the Drosophila adult midgut

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Gene name Irp-1B
Flybase description The gene Iron regulatory protein 1B is referred to in FlyBase by the symbol Dmel\Irp-1B (CG6342, FBgn0024957).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 2.3839 2.7107 1.732945 1.3305 -1.870078 0.4232 2.75084 0.408902
    Affimetrix absolute value 9.616 9.053 8.93 8.795 7.895 8.677 10.0 8.342
    Affymetric present call in "x" number of chips 3 3 3 3 3 3 3 3
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
There is experimental evidence that it has the molecular function: iron-responsive element binding; aconitate hydratase activity.
It is reported to be involved in the biological process: regulation of translational initiation by iron.
6 alleles are reported.
No phenotypic data is available.
It has one annotated transcript and one annotated polypeptide.
Protein features are: Aconitase A/isopropylmalate dehydratase small subunit, swivel; Aconitase family, 4Fe-4S cluster binding site; Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha; Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3; Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 2; Aconitase/3-isopropylmalate dehydratase, swivel; Aconitase/Iron regulatory protein 2/2-methylisocitrate dehydratase; Aconitase/iron regulatory protein 2; Aconitase/isopropylmalate dehydratase.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of low expression.
Peak expression observed at stages throughout the larval period, during early pupal stages.
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