Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
Search expression data by gene:
Gene name GRHR
Flybase description The gene Gonadotropin-releasing hormone receptor is referred to in FlyBase by the symbol Dmel\GRHR (CG11325, FBgn0025595).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -63.1919 -43.1812 -67.480516 -70.1689 -93.192528 -82.5418 -71.85548 -61.161952
    Affimetrix absolute value 2.427 2.196 2.104 2.261 2.217 2.197 2.394 2.345
    Affymetric present call in "x" number of chips 0 0 0 0 0 0 0 0
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
There is experimental evidence that it has the molecular function: adipokinetic hormone binding; peptide receptor activity; adipokinetic hormone receptor activity.
There is experimental evidence that it is involved in the biological process: triglyceride homeostasis; lipid homeostasis; G-protein coupled receptor protein signaling pathway; lipid catabolic process; carbohydrate homeostasis.
16 alleles are reported.
The phenotypes of these alleles are annotated with: adult fat body; lipid droplet.
It has 3 annotated transcripts and 3 annotated polypeptides.
Protein features are: GPCR, rhodopsin-like superfamily; GPCR, rhodopsin-like, 7TM.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of extremely low expression.
Peak expression observed during late larval stages, during early pupal stages.
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