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Gene name | skpA | ||||||||||||||||||||||||||||||||||||
Flybase description | The gene skpA is referred to in FlyBase by the symbol Dmel\skpA (CG16983, FBgn0025637). | ||||||||||||||||||||||||||||||||||||
Expression data along the gut |
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Intestinal gene expression in different physiological conditions |
Ecc15: flies orally infected with Erwinia carotovora carotovora 15. Pe: flies orally infected with Pseudomonas entomophila. Pe gacA: flies orally infecte with Pseudomonas entomophila gacA. For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe. |
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Gene details (from Flybase) | It is a protein_coding_gene from Drosophila melanogaster. There is experimental evidence that it has the molecular function: protein binding. There is experimental evidence that it is involved in the biological process: regulation of protein stability; regulation of centrosome duplication; mitotic cell cycle G2/M transition DNA damage checkpoint; mitosis; centrosome duplication; chromosome condensation; DNA endoreduplication; neurogenesis; positive regulation of mitotic cell cycle. 27 alleles are reported. The phenotypes of these alleles are annotated with: embryonic/larval digestive system; imaginal disc; melanotic mass; chromatin; embryonic/larval central nervous system. It has 8 annotated transcripts and 8 annotated polypeptides. Protein features are: BTB/POZ fold; E3 ubiquitin ligase, SCF complex, Skp subunit; SKP1 component; SKP1 component, POZ; SKP1 component, dimerisation. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of moderately high expression. Peak expression observed at stages throughout embryogenesis, during early pupal stages, in adult female stages. . |