Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
Search expression data by gene:
Gene name DAAM
Flybase description The gene Dishevelled Associated Activator of Morphogenesis is referred to in FlyBase by the symbol Dmel\DAAM (CG14622, FBgn0025641).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -27.5678 -16.594 -22.55448 -22.4198 -38.273516 -31.7305 -39.21477 -30.192924
    Affimetrix absolute value 3.627 3.587 3.69 3.902 3.514 3.58 3.262 3.37
    Affymetric present call in "x" number of chips 2 3 2 2 2 2 1 0
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
Based on sequence similarity, it is predicted to have molecular function: actin binding.
There is experimental evidence that it is involved in the biological process: actin filament bundle assembly; regulation of axonogenesis; positive regulation of filopodium assembly; regulation of filopodium assembly; regulation of tube architecture, open tracheal system; open tracheal system development.
23 alleles are reported.
The phenotypes of these alleles are annotated with 14 unique terms, many of which group under: organ system; multicellular structure; anatomical structure; organ system subdivision; tracheal system; cell part; portion of tissue; cell projection; acellular anatomical structure; organelle.
It has 4 annotated transcripts and 4 annotated polypeptides.
Protein features are: Actin-binding FH2; Actin-binding FH2/DRF autoregulatory; Armadillo-type fold; Diaphanous FH3; Diaphanous GTPase-binding; Diaphanous autoregulatory; GTPase-binding/formin homology 3.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of low expression.
Peak expression observed within 00-06 and 12-18 hour embryonic stages.
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