Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
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Gene name plexA
Flybase description The gene plexin A is referred to in FlyBase by the symbol Dmel\plexA (CG11081, FBgn0025741).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -1.8983 -0.3803 -2.210612 0.3922 -3.817999 -1.6918 -2.21349 -2.387185
    Affimetrix absolute value 7.524 7.558 7.035 8.464 6.869 7.812 7.439 7.082
    Affymetric present call in "x" number of chips 3 3 3 3 3 3 3 3
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
There is experimental evidence that it has the molecular function: protein binding.
There is experimental evidence that it is involved in the biological process: axon guidance; semaphorin-plexin signaling pathway involved in regulation of photoreceptor cell axon guidance; axon midline choice point recognition.
15 alleles are reported.
The phenotypes of these alleles are annotated with: ventral nerve cord; adult olfactory receptor neuron Or33c/85e; adult olfactory receptor neuron Or42a; intersegmental nerve; longitudinal connective; presumptive embryonic/larval central nervous system; abdominal segmental nerve; abdominal intersegmental nerve; transverse nerve; adult olfactory receptor neuron Or46a.
It has 6 annotated transcripts and 6 annotated polypeptides.
Protein features are: Cell surface receptor IPT/TIG; Immunoglobulin E-set; Immunoglobulin-like fold; Plexin; Plexin, cytoplasmic RasGAP domain; Plexin-like fold; Plexin/semaphorin/integrin; Rho GTPase activation protein; Semaphorin/CD100 antigen; WD40/YVTN repeat-like-containing domain.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of moderate expression.
Peak expression observed within 00-06 and 12-18 hour embryonic stages.
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