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Gene name | plexA | ||||||||||||||||||||||||||||||||||||
Flybase description | The gene plexin A is referred to in FlyBase by the symbol Dmel\plexA (CG11081, FBgn0025741). | ||||||||||||||||||||||||||||||||||||
Expression data along the gut |
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Intestinal gene expression in different physiological conditions |
Ecc15: flies orally infected with Erwinia carotovora carotovora 15. Pe: flies orally infected with Pseudomonas entomophila. Pe gacA: flies orally infecte with Pseudomonas entomophila gacA. For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe. |
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Gene details (from Flybase) | It is a protein_coding_gene from Drosophila melanogaster. There is experimental evidence that it has the molecular function: protein binding. There is experimental evidence that it is involved in the biological process: axon guidance; semaphorin-plexin signaling pathway involved in regulation of photoreceptor cell axon guidance; axon midline choice point recognition. 15 alleles are reported. The phenotypes of these alleles are annotated with: ventral nerve cord; adult olfactory receptor neuron Or33c/85e; adult olfactory receptor neuron Or42a; intersegmental nerve; longitudinal connective; presumptive embryonic/larval central nervous system; abdominal segmental nerve; abdominal intersegmental nerve; transverse nerve; adult olfactory receptor neuron Or46a. It has 6 annotated transcripts and 6 annotated polypeptides. Protein features are: Cell surface receptor IPT/TIG; Immunoglobulin E-set; Immunoglobulin-like fold; Plexin; Plexin, cytoplasmic RasGAP domain; Plexin-like fold; Plexin/semaphorin/integrin; Rho GTPase activation protein; Semaphorin/CD100 antigen; WD40/YVTN repeat-like-containing domain. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of moderate expression. Peak expression observed within 00-06 and 12-18 hour embryonic stages. . |