Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
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Gene name mtm
Flybase description The gene myotubularin is referred to in FlyBase by the symbol Dmel\mtm (CG9115, FBgn0025742).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -2.0877 -1.0681 -1.111903 -1.254 -1.411099 -1.7326 -1.73176 -1.220722
    Affimetrix absolute value 7.354 7.525 8.024 8.066 8.265 7.796 7.771 7.953
    Affymetric present call in "x" number of chips 3 3 3 3 3 3 3 3
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
There is experimental evidence that it has the molecular function: inositol or phosphatidylinositol phosphatase activity.
There is experimental evidence that it is involved in the biological process: mitotic cell cycle; cell projection assembly; chromosome segregation; response to wounding.
9 alleles are reported.
The phenotypes of these alleles are annotated with: sessile hemocyte; embryonic/larval hemocyte.
It has one annotated transcript and one annotated polypeptide.
Protein features are: GRAM; Myotubularin phosphatase domain; Myotubularin-related; Protein-tyrosine phosphatase, active site.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of moderate expression.
Peak expression observed within 06-18 hour embryonic stages.
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