Flygut: an atlas of the Drosophila adult midgut

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Gene name Paf-AHalpha
Flybase description The gene Platelet-activating factor acetylhydrolase alpha is referred to in FlyBase by the symbol Dmel\Paf-AHα (CG8962, FBgn0025809).
Expression data along the gut
    Created with Highcharts 6.0.3Fold change compared to full gutRegion-specific expression of Paf-AHalpha along the gutCropCardia/R1R2R3R4R5Hindgut012345Highcharts.com
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -2.1978 -2.7119 -6.803493 -4.6575 -9.998424 -6.0226 -4.42257 -7.806245
    Affimetrix absolute value 7.276 6.181 5.435 6.176 5.461 5.984 6.441 5.331
    Affymetric present call in "x" number of chips 3 3 3 3 3 3 3 3
Intestinal gene expression in different physiological conditions
Created with Highcharts 6.0.3Fold change compared toUnchallengedFold change compared to UnchallengedExpression of Paf-AHalpha in different experimental conditionsEcc15 4hEcc15 16hPe 4hPe 16hPe gacA 4hPe gacA 16h-2-1012Highcharts.com
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
Based on sequence similarity, it is predicted to have molecular function: 1-alkyl-2-acetylglycerophosphocholine esterase activity.
The biological processes in which it is involved are not known.
3 alleles are reported.
No phenotypic data is available.
It has 2 annotated transcripts and 2 annotated polypeptides.
Protein features are: Esterase, SGNH hydrolase-type; Esterase, SGNH hydrolase-type, subgroup.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of moderate expression.
Peak expression observed within 00-12 hour embryonic stages.
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