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| Gene name | Cortactin | ||||||||||||||||||||||||||||||||||||
| Flybase description | The gene Cortactin is referred to in FlyBase by the symbol Dmel\Cortactin (CG3637, FBgn0025865). | ||||||||||||||||||||||||||||||||||||
| Expression data along the gut |
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| Intestinal gene expression in different physiological conditions |
Ecc15: flies orally infected with Erwinia carotovora carotovora 15. Pe: flies orally infected with Pseudomonas entomophila. Pe gacA: flies orally infecte with Pseudomonas entomophila gacA. For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe. |
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| Gene details (from Flybase) | It is a protein_coding_gene from Drosophila melanogaster. There is experimental evidence that it has the molecular function: proline-rich region binding. There is experimental evidence that it is involved in the biological process: regulation of cell shape; positive regulation of receptor-mediated endocytosis; border follicle cell migration; female germline ring canal formation. 19 alleles are reported. The phenotypes of these alleles are annotated with: nurse follicle cell; nurse cell ring canal; egg; border follicle cell. It has 4 annotated transcripts and 4 annotated polypeptides. Protein features are: Cortactin; Hs1/Cortactin; Neutrophil cytosol factor 2 p67phox; Src homology-3 domain. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of moderate expression. Peak expression observed within 00-12 hour embryonic stages, during late larval stages, during early pupal stages. . |
