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| Gene name | Timp | ||||||||||||||||||||||||||||||||||||
| Flybase description | The gene Tissue inhibitor of metalloproteases is referred to in FlyBase by the symbol Dmel\Timp (CG6281, FBgn0025879). | ||||||||||||||||||||||||||||||||||||
| Expression data along the gut |
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| Intestinal gene expression in different physiological conditions |
Ecc15: flies orally infected with Erwinia carotovora carotovora 15. Pe: flies orally infected with Pseudomonas entomophila. Pe gacA: flies orally infecte with Pseudomonas entomophila gacA. For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe. |
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| Gene details (from Flybase) | It is a protein_coding_gene from Drosophila melanogaster. There is experimental evidence that it has the molecular function: metalloendopeptidase inhibitor activity. There is experimental evidence that it is involved in the biological process: tracheal pit formation in open tracheal system; wing disc morphogenesis; phototaxis; delamination; imaginal disc-derived wing expansion; tracheal outgrowth, open tracheal system; cell adhesion; basement membrane organization. 7 alleles are reported. The phenotypes of these alleles are annotated with: dorsal air sac; adult abdomen; embryonic/larval dorsal trunk; wing. It has one annotated transcript and one annotated polypeptide. Protein features are: Netrin domain; Proteinase inhibitor I35, tissue inhibitor of metalloproteinase; Tissue inhibitor of metalloproteinases-like, OB-fold. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of extremely low expression. Peak expression observed during early pupal stages, in adult male stages. . |
