Flygut: an atlas of the Drosophila adult midgut

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Gene name Eph
Flybase description The gene Eph receptor tyrosine kinase is referred to in FlyBase by the symbol Dmel\Eph (CG1511, FBgn0025936).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -1.8996 -0.4032 -3.504156 -2.5663 -5.403771 -2.0771 -2.35018 -4.458576
    Affimetrix absolute value 7.509 7.526 6.432 7.049 6.414 7.512 7.338 6.298
    Affymetric present call in "x" number of chips 3 3 3 3 3 3 3 3
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
Based on sequence similarity, it is predicted to have molecular function: ephrin receptor activity; transmembrane receptor protein tyrosine kinase activity.
There is experimental evidence that it is involved in the biological process: mushroom body development.
17 alleles are reported.
The phenotypes of these alleles are annotated with: medulla neuropil; commissure; fascicle; lobula plate cortex; cortex of medulla; longitudinal connective; mushroom body medial lobe; mushroom body vertical lobe; embryonic/larval optic lobe; embryonic/larval neuron.
It has 6 annotated transcripts and 6 annotated polypeptides.
Protein features are: Ephrin receptor, ligand binding; Fibronectin type III domain; Fibronectin, type III; Galactose-binding domain-like; Growth factor, receptor; Immunoglobulin-like fold; Protein kinase, ATP binding site; Protein kinase, catalytic domain; Protein kinase-like domain; Serine-threonine/tyrosine-protein kinase; Sterile alpha motif domain; Sterile alpha motif homology; Sterile alpha motif, type 1; Sterile alpha motif-type; Tyrosine-protein kinase, active site; Tyrosine-protein kinase, catalytic domain; Tyrosine-protein kinase, ephrin receptor; Tyrosine-protein kinase, ephrin receptor Dek-like; Tyrosine-protein kinase, receptor class V, conserved site.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of moderate expression.
Peak expression observed within 00-06 and 12-18 hour embryonic stages.
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