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| Gene name | Top3beta | ||||||||||||||||||||||||||||||||||||
| Flybase description | The gene Topoisomerase 3β is referred to in FlyBase by the symbol Dmel\Top3β (CG3458, FBgn0026015). | ||||||||||||||||||||||||||||||||||||
| Expression data along the gut |
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| Intestinal gene expression in different physiological conditions |
Ecc15: flies orally infected with Erwinia carotovora carotovora 15. Pe: flies orally infected with Pseudomonas entomophila. Pe gacA: flies orally infecte with Pseudomonas entomophila gacA. For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe. |
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| Gene details (from Flybase) | It is a protein_coding_gene from Drosophila melanogaster. There is experimental evidence that it has the molecular function: DNA topoisomerase activity; endodeoxyribonuclease activity. There is experimental evidence that it is involved in the biological process: DNA catabolic process, endonucleolytic. 15 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. Protein features are: DNA topoisomerase, type IA; DNA topoisomerase, type IA, DNA-binding; DNA topoisomerase, type IA, active site; DNA topoisomerase, type IA, central; DNA topoisomerase, type IA, central region, subdomain 1; DNA topoisomerase, type IA, central region, subdomain 2; DNA topoisomerase, type IA, core domain; DNA topoisomerase, type IA, domain 2; Toprim domain. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of moderate expression. Peak expression observed within 00-06 hour embryonic stages. . |
