Flygut: an atlas of the Drosophila adult midgut

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Gene name Adar
Flybase description The gene Adenosine deaminase acting on RNA is referred to in FlyBase by the symbol Dmel\Adar (CG12598, FBgn0026086).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -31.415 -16.0858 -25.839292 -22.1911 -43.94934 -27.8826 -19.22243 -31.245622
    Affimetrix absolute value 3.466 3.632 3.487 3.925 3.311 3.78 4.292 3.295
    Affymetric present call in "x" number of chips 0 3 1 3 0 0 3 0
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
There is experimental evidence that it has the molecular function: double-stranded RNA adenosine deaminase activity.
There is experimental evidence that it is involved in the biological process: response to hypoxia; adult behavior; locomotory behavior; adenosine to inosine editing; adult locomotory behavior; response to heat; mRNA modification; regulation of membrane potential.
29 alleles are reported.
The phenotypes of these alleles are annotated with 11 unique terms, many of which group under: organ system subdivision; organ system; adult segment; adult; multicellular structure; protocerebrum; eo support cell; thoracic segment; external compound sense organ; sense organ; integumentary plate; peripheral nervous system.
It has 12 annotated transcripts and 12 annotated polypeptides.
Protein features are: Adenosine deaminase/editase; Double-stranded RNA-binding; Double-stranded RNA-binding-like.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of low expression.
Peak expression observed within 00-18 hour embryonic stages, at stages throughout the pupal period.
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