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Gene name | CDC45L | ||||||||||||||||||||||||||||||||||||
Flybase description | The gene CDC45L is referred to in FlyBase by the symbol Dmel\CDC45L (CG3658, FBgn0026143). | ||||||||||||||||||||||||||||||||||||
Expression data along the gut |
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Intestinal gene expression in different physiological conditions |
Ecc15: flies orally infected with Erwinia carotovora carotovora 15. Pe: flies orally infected with Pseudomonas entomophila. Pe gacA: flies orally infecte with Pseudomonas entomophila gacA. For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe. |
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Gene details (from Flybase) | It is a protein_coding_gene from Drosophila melanogaster. There is experimental evidence that it has the molecular function: 3'-5' DNA helicase activity; chromatin binding. There is experimental evidence that it is involved in the biological process: DNA amplification; mitotic cell cycle G2/M transition DNA damage checkpoint; DNA replication; positive regulation of S phase of mitotic cell cycle; chromosome condensation; neurogenesis. 6 alleles are reported. The phenotypes of these alleles are annotated with: trichogen cell; nuclear chromosome; mesothoracic tergum. It has one annotated transcript and one annotated polypeptide. Protein features are: CDC45 family. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of low expression. Peak expression observed within 00-06 hour embryonic stages, in adult female stages. . |