Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
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Gene name skpD
Flybase description The gene skpD is referred to in FlyBase by the symbol Dmel\skpD (CG12700, FBgn0026174).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -38.2661 -30.8156 -44.584002 -43.6767 -51.840855 -46.6969 -52.97732 -45.644065
    Affimetrix absolute value 3.166 2.685 2.706 2.945 3.115 3.022 2.831 2.811
    Affymetric present call in "x" number of chips 0 0 0 0 0 0 0 0
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
Its molecular function is unknown.
An electronic pipeline based on InterPro domains suggests that it is involved in the biological process: ubiquitin-dependent protein catabolic process.
3 alleles are reported.
The phenotype of these alleles is annotated with: mesothoracic tergum.
It has one annotated transcript and one annotated polypeptide.
Protein features are: BTB/POZ fold; E3 ubiquitin ligase, SCF complex, Skp subunit; SKP1 component; SKP1 component, POZ; SKP1 component, dimerisation.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderate expression to a trough of no expression detected.
Peak expression observed at stages throughout the pupal period, in adult male stages.
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