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| Gene name | siz | ||||||||||||||||||||||||||||||||||||
| Flybase description | The gene schizo is referred to in FlyBase by the symbol Dmel\siz (CG32434, FBgn0026179). | ||||||||||||||||||||||||||||||||||||
| Expression data along the gut |
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| Intestinal gene expression in different physiological conditions |
Ecc15: flies orally infected with Erwinia carotovora carotovora 15. Pe: flies orally infected with Pseudomonas entomophila. Pe gacA: flies orally infecte with Pseudomonas entomophila gacA. For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe. |
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| Gene details (from Flybase) | It is a protein_coding_gene from Drosophila melanogaster. Based on sequence similarity, it is predicted to have molecular function: guanyl-nucleotide exchange factor activity. There is experimental evidence that it is involved in the biological process: myoblast fusion; central nervous system development; inter-male aggressive behavior; actin cytoskeleton organization. 52 alleles are reported. The phenotypes of these alleles are annotated with: commissure; ventral nerve cord commissure; midline glial cell; embryonic myoblast. It has 4 annotated transcripts and 4 annotated polypeptides. Protein features are: IQ motif, EF-hand binding site; Pleckstrin homology domain; Pleckstrin homology-type; SEC7-like; SEC7-like, alpha orthogonal bundle. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of moderate expression. Peak expression observed within 00-12 hour embryonic stages. . |
