Flygut: an atlas of the Drosophila adult midgut

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Gene name rok
Flybase description The gene Rho-kinase is referred to in FlyBase by the symbol Dmel\rok (CG9774, FBgn0026181).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -6.5425 -1.8472 -2.694734 -2.361 -5.500263 -3.1334 -5.11509 -4.515721
    Affimetrix absolute value 5.698 6.763 6.753 7.166 6.331 6.928 6.258 6.105
    Affymetric present call in "x" number of chips 3 3 3 3 3 3 3 3
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
There is experimental evidence that it has the molecular function: GTPase binding; protein binding; protein serine/threonine kinase activity.
There is experimental evidence for 26 unique biological process terms, many of which group under: biological regulation; cellular component organization or biogenesis; localization; ovarian nurse cell to oocyte transport; multicellular organism reproduction; cell cycle; regulation of developmental process; establishment of planar polarity; regulation of cellular component organization; gamete generation.
23 alleles are reported.
The phenotypes of these alleles are annotated with 12 unique terms, many of which group under: organ system; organ system subdivision; adult segment; portion of tissue; non-connected developing system; epithelial cell; nucleus; external compound sense organ; embryonic foregut; thoracic segment.
It has one annotated transcript and one annotated polypeptide.
Protein features are: AGC-kinase, C-terminal; Pleckstrin homology domain; Pleckstrin homology-type; Protein kinase C-like, phorbol ester/diacylglycerol binding; Protein kinase, ATP binding site; Protein kinase, C-terminal; Protein kinase, catalytic domain; Protein kinase-like domain; Rho Binding; Rho-associated coiled-coil containing protein kinase; Serine/threonine-protein kinase domain; Serine/threonine-protein kinase, active site; Serine/threonine-protein kinase-like domain.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of moderate expression.
Peak expression observed within 00-18 hour embryonic stages, during late larval stages, during early pupal stages, in adult female stages.
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