Flygut: an atlas of the Drosophila adult midgut

 Mouche Logo lab lemaitre Bbcf logo
Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
Search expression data by gene:
Gene name eIF-1A
Flybase description The gene Eukaryotic initiation factor 1A is referred to in FlyBase by the symbol Dmel\eIF-1A (CG8053, FBgn0026250).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 6.7374 7.13 4.371606 4.7792 2.242686 3.6943 6.10015 3.630218
    Affimetrix absolute value 11.152 10.43 10.277 10.639 9.902 10.447 11.142 10.034
    Affymetric present call in "x" number of chips 3 3 3 3 3 3 3 3
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
Based on sequence similarity, it is predicted to have molecular function: translation initiation factor activity.
There is experimental evidence that it is involved in the biological process: smoothened signaling pathway; mitotic spindle elongation; mitotic spindle organization; phagocytosis, engulfment.
14 alleles are reported.
No phenotypic data is available.
It has 2 annotated transcripts and 2 annotated polypeptides.
Protein features are: Nucleic acid-binding, OB-fold; Nucleic acid-binding, OB-fold-like; RNA-binding domain, S1, IF1 type; Translation initiation factor 1A (eIF-1A); Translation initiation factor 1A (eIF-1A), conserved site.
Summary of modENCODE Temporal Expression Profile: Very high expression at all stages of development.
.