Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
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Gene name Tom
Flybase description The gene Twin of m4 is referred to in FlyBase by the symbol Dmel\Tom (CG5185, FBgn0026320).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -61.4403 -27.6147 -47.15631 -48.7313 -59.323004 -52.5411 -49.99674 -53.756677
    Affimetrix absolute value 2.469 2.96 2.648 2.794 2.871 2.854 2.923 2.568
    Affymetric present call in "x" number of chips 0 1 0 0 0 0 0 0
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
Its molecular function is unknown.
There is experimental evidence that it is involved in the biological process: sensory organ precursor cell fate determination; sensory organ development; establishment of planar polarity; Notch signaling pathway; cell fate specification.
12 alleles are reported.
The phenotypes of these alleles are annotated with 18 unique terms, many of which group under: organ system subdivision; organ system; external compound sense organ; adult segment; peripheral nervous system; hypodermal muscle of larval abdomen; larval abdominal segment; thoracic segment; cardioblast; wing margin bristle; integumentary plate.
It has one annotated transcript and one annotated polypeptide.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of extremely high expression to a trough of extremely low expression.
Peak expression observed within 00-06 hour embryonic stages.
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