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Gene name | SAK | ||||||||||||||||||||||||||||||||||||
Flybase description | The gene Sak kinase is referred to in FlyBase by the symbol Dmel\SAK (CG7186, FBgn0026371). | ||||||||||||||||||||||||||||||||||||
Expression data along the gut |
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Intestinal gene expression in different physiological conditions |
Ecc15: flies orally infected with Erwinia carotovora carotovora 15. Pe: flies orally infected with Pseudomonas entomophila. Pe gacA: flies orally infecte with Pseudomonas entomophila gacA. For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe. |
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Gene details (from Flybase) | It is a protein_coding_gene from Drosophila melanogaster. Based on sequence similarity, it is predicted to have molecular function: protein serine/threonine kinase activity. There is experimental evidence that it is involved in the biological process: centrosome organization; sperm axoneme assembly; mitotic spindle organization; centriole replication; centrosome duplication; regulation of centriole replication. 12 alleles are reported. The phenotypes of these alleles are annotated with: centriole; ventral nerve cord; presumptive embryonic/larval peripheral nervous system; spermatid; centrosome; longitudinal connective; spermatid axoneme; spermatocyte; spermatozoon. It has one annotated transcript and one annotated polypeptide. Protein features are: POLO box duplicated domain; Protein kinase, ATP binding site; Protein kinase, catalytic domain; Protein kinase-like domain; Serine/threonine-protein kinase domain; Serine/threonine-protein kinase-like domain; Tyrosine-protein kinase, active site. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of very low expression. Peak expression observed within 00-12 hour embryonic stages. . |