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Gene name | Nc | ||||||||||||||||||||||||||||||||||||
Flybase description | The gene Nedd2-like caspase is referred to in FlyBase by the symbol Dmel\Nc (CG8091, FBgn0026404). | ||||||||||||||||||||||||||||||||||||
Expression data along the gut |
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Intestinal gene expression in different physiological conditions |
Ecc15: flies orally infected with Erwinia carotovora carotovora 15. Pe: flies orally infected with Pseudomonas entomophila. Pe gacA: flies orally infecte with Pseudomonas entomophila gacA. For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe. |
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Gene details (from Flybase) | It is a protein_coding_gene from Drosophila melanogaster. There is experimental evidence that it has the molecular function: endopeptidase activity; cysteine-type endopeptidase activity; protein homodimerization activity. There is experimental evidence for 19 unique biological process terms, many of which group under: programmed cell death; cell death; system development; protein maturation; biological regulation; gland morphogenesis; sensory organ development; neuron differentiation; gene expression; salivary gland morphogenesis. 67 alleles are reported. The phenotypes of these alleles are annotated with 18 unique terms, many of which group under: organ system; organ system subdivision; external compound sense organ; peripheral nervous system; cell part; embryonic/larval excretory system; imaginal precursor; adult segment; adult; pigment cell; acellular anatomical structure; cell projection. It has one annotated transcript and one annotated polypeptide. Protein features are: Caspase, interleukin-1 beta convertase; DEATH-like; Peptidase C14, ICE, catalytic subunit p20; Peptidase C14, ICE, catalytic subunit p20, active site; Peptidase C14, caspase catalytic; Peptidase C14, caspase non-catalytic subunit p10; Peptidase C14, caspase precursor p45; Peptidase C14, caspase precursor p45, core. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of low expression. Peak expression observed at stages throughout the pupal period. . |