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Gene name | Eaat1 | ||||||||||||||||||||||||||||||||||||
Flybase description | The gene Excitatory amino acid transporter 1 is referred to in FlyBase by the symbol Dmel\Eaat1 (CG3747, FBgn0026439). | ||||||||||||||||||||||||||||||||||||
Expression data along the gut |
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Intestinal gene expression in different physiological conditions |
Ecc15: flies orally infected with Erwinia carotovora carotovora 15. Pe: flies orally infected with Pseudomonas entomophila. Pe gacA: flies orally infecte with Pseudomonas entomophila gacA. For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe. |
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Gene details (from Flybase) | It is a protein_coding_gene from Drosophila melanogaster. There is experimental evidence that it has the molecular function: L-glutamate transmembrane transporter activity; glutamate:sodium symporter activity; L-aspartate transmembrane transporter activity. There is experimental evidence that it is involved in the biological process: determination of adult lifespan; regulation of excitatory postsynaptic membrane potential involved in skeletal muscle contraction. 12 alleles are reported. The phenotypes of these alleles are annotated with: neuromuscular junction; neuropil; dopaminergic neuron; adult neuromuscular junction; synapse. It has 4 annotated transcripts and 4 annotated polypeptides. Protein features are: Sodium:dicarboxylate symporter; Sodium:dicarboxylate symporter, conserved site. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of very low expression. Peak expression observed during late pupal stages. . |