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Gene name | Axn | ||||||||||||||||||||||||||||||||||||
Flybase description | The gene Axin is referred to in FlyBase by the symbol Dmel\Axn (CG7926, FBgn0026597). | ||||||||||||||||||||||||||||||||||||
Expression data along the gut |
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Intestinal gene expression in different physiological conditions |
Ecc15: flies orally infected with Erwinia carotovora carotovora 15. Pe: flies orally infected with Pseudomonas entomophila. Pe gacA: flies orally infecte with Pseudomonas entomophila gacA. For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe. |
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Gene details (from Flybase) | It is a protein_coding_gene from Drosophila melanogaster. There is experimental evidence that it has the molecular function: beta-catenin binding; protein kinase binding. There is experimental evidence that it is involved in the biological process: imaginal disc pattern formation; eye-antennal disc morphogenesis; somatic stem cell maintenance; negative regulation of Wnt receptor signaling pathway; oogenesis; imaginal disc-derived wing morphogenesis; Wnt receptor signaling pathway; phagocytosis, engulfment. 40 alleles are reported. The phenotypes of these alleles are annotated with 19 unique terms, many of which group under: organ system; adult segment; organ system subdivision; thoracic segment; portion of tissue; acellular anatomical structure; tracheal system; indirect flight muscle; adult; external compound sense organ. It has 5 annotated transcripts and 5 annotated polypeptides. Protein features are: Axin beta-catenin binding; DIX; Regulator of G protein signalling; Regulator of G protein signalling superfamily; Regulator of G-protein signaling, domain 1. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of moderate expression. Peak expression observed within 00-06 hour embryonic stages. . |