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Gene name | Apc2 | ||||||||||||||||||||||||||||||||||||
Flybase description | The gene Adenomatous polyposis coli tumor suppressor homolog 2 is referred to in FlyBase by the symbol Dmel\Apc2 (CG6193, FBgn0026598). | ||||||||||||||||||||||||||||||||||||
Expression data along the gut |
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Intestinal gene expression in different physiological conditions |
Ecc15: flies orally infected with Erwinia carotovora carotovora 15. Pe: flies orally infected with Pseudomonas entomophila. Pe gacA: flies orally infecte with Pseudomonas entomophila gacA. For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe. |
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Gene details (from Flybase) | It is a protein_coding_gene from Drosophila melanogaster. There is experimental evidence that it has the molecular function: protein binding. There is experimental evidence for 16 unique biological process terms, many of which group under: system development; multicellular organismal development; embryonic development via the syncytial blastoderm; cellular process; cellular component organization or biogenesis; localization; biological regulation; embryo development ending in birth or egg hatching; cell adhesion; chitin-based cuticle development; regulation of Wnt receptor signaling pathway. 28 alleles are reported. The phenotypes of these alleles are annotated with 17 unique terms, many of which group under: organ system; multicellular structure; non-connected developing system; portion of tissue; late extended germ band embryo; acellular anatomical structure; organ system subdivision; anatomical structure; extended germ band embryo; ovariole; cell part; adherens junction; embryonic/larval integumentary system; external compound sense organ; adult segment. It has one annotated transcript and one annotated polypeptide. Protein features are: Adenomatous polyposis coli protein, 15 residue repeat; Adenomatous polyposis coli protein, cysteine-rich repeat; Armadillo; Armadillo-like helical; Armadillo-type fold. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of low expression. Peak expression observed within 00-06 hour embryonic stages. . |