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Gene name | XRCC1 | ||||||||||||||||||||||||||||||||||||
Flybase description | The gene XRCC1 is referred to in FlyBase by the symbol Dmel\XRCC1 (CG4208, FBgn0026751). | ||||||||||||||||||||||||||||||||||||
Expression data along the gut |
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Intestinal gene expression in different physiological conditions |
Ecc15: flies orally infected with Erwinia carotovora carotovora 15. Pe: flies orally infected with Pseudomonas entomophila. Pe gacA: flies orally infecte with Pseudomonas entomophila gacA. For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe. |
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Gene details (from Flybase) | It is a protein_coding_gene from Drosophila melanogaster. An electronic pipeline based on InterPro domains suggests that it has the molecular function: damaged DNA binding. There is experimental evidence that it is involved in the biological process: base-excision repair, AP site formation; lateral inhibition; response to DNA damage stimulus. 2 alleles are reported. The phenotypes of these alleles are annotated with: trichogen cell; chaeta. It has one annotated transcript and one annotated polypeptide. Protein features are: BRCT; DNA-repair protein Xrcc1, N-terminal; Galactose-binding domain-like. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of low expression. Peak expression observed within 00-12 hour embryonic stages, in adult female stages. . |