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Gene name | Nhe1 | ||||||||||||||||||||||||||||||||||||
Flybase description | The gene Na+/H+ hydrogen exchanger 1 is referred to in FlyBase by the symbol Dmel\Nhe1 (CG12178, FBgn0026787). | ||||||||||||||||||||||||||||||||||||
Expression data along the gut |
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Intestinal gene expression in different physiological conditions |
Ecc15: flies orally infected with Erwinia carotovora carotovora 15. Pe: flies orally infected with Pseudomonas entomophila. Pe gacA: flies orally infecte with Pseudomonas entomophila gacA. For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe. |
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Gene details (from Flybase) | It is a protein_coding_gene from Drosophila melanogaster. Based on sequence similarity, it is predicted to have molecular function: sodium:hydrogen antiporter activity. An electronic pipeline based on InterPro domains suggests that it is involved in the biological process: transmembrane transport; sodium ion transport; regulation of pH. 4 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. Protein features are: Cation/H+ exchanger; Cation/H+ exchanger, CPA1 family; Na+/H+ exchanger; Na+/H+ exchanger, isoform 8, eukaryotic. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of moderate expression. Peak expression observed within 00-06 hour embryonic stages, during late larval stages, in stages of adults of both sexes. . |