Flygut: an atlas of the Drosophila adult midgut

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Gene name Thd1
Flybase description The gene Thd1 is referred to in FlyBase by the symbol Dmel\Thd1 (CG1981, FBgn0026869).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -25.9523 -15.8283 -19.759725 -24.7249 -30.64637 -30.9178 -24.96379 -21.84892
    Affimetrix absolute value 3.728 3.649 3.924 3.776 3.839 3.611 3.925 3.838
    Affymetric present call in "x" number of chips 0 0 0 0 0 0 0 0
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
There is experimental evidence that it has the molecular function: pyrimidine-specific mismatch base pair DNA N-glycosylase activity; double-stranded DNA binding.
There is experimental evidence that it is involved in the biological process: mismatch repair; response to DNA damage stimulus.
5 alleles are reported.
No phenotypic data is available.
It has one annotated transcript and one annotated polypeptide.
Protein features are: AT hook, DNA-binding motif; DNA glycosylase, G/T mismatch; Uracil-DNA glycosylase-like.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of moderate expression.
Peak expression observed within 12-24 hour embryonic stages, during late larval stages, at stages throughout the pupal period.
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