Flygut: an atlas of the Drosophila adult midgut

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Gene name Kap-alpha3
Flybase description The gene karyopherin α3 is referred to in FlyBase by the symbol Dmel\Kap-α3 (CG9423, FBgn0027338).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -11.2503 -10.568 -15.948103 -17.7054 -27.746457 -21.0413 -16.30242 -16.92228
    Affimetrix absolute value 4.939 4.232 4.182 4.252 3.985 4.169 4.535 4.168
    Affymetric present call in "x" number of chips 3 2 0 0 0 0 2 0
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
There is experimental evidence that it has the molecular function: protein binding.
There is experimental evidence that it is involved in the biological process: mitotic cell cycle G2/M transition DNA damage checkpoint; positive regulation of NFAT protein import into nucleus; response to UV.
18 alleles are reported.
The phenotypes of these alleles are annotated with: photoreceptor cell R7; mesothoracic tergum; tormogen cell; tergite.
It has 4 annotated transcripts and 4 annotated polypeptides.
Protein features are: Armadillo; Armadillo-like helical; Armadillo-type fold; Importin-alpha-like, importin-beta-binding domain.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of high expression.
Peak expression observed within 00-12 and 18-24 hour embryonic stages, in adult female stages.
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