Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
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Gene name Stam
Flybase description The gene Signal transducing adaptor molecule is referred to in FlyBase by the symbol Dmel\Stam (CG6521, FBgn0027363).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -3.0124 1.6178 0.563838 1.2302 -1.39456 -0.5198 -2.12111 0.186696
    Affimetrix absolute value 6.827 8.302 8.454 8.667 8.316 8.332 7.511 8.103
    Affymetric present call in "x" number of chips 3 3 3 3 3 3 3 3
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
It is reported to have molecular function: JAK pathway signal transduction adaptor activity.
There is experimental evidence that it is involved in the biological process: epithelial cell migration, open tracheal system.
7 alleles are reported.
The phenotype of these alleles is annotated with: trichogen cell.
It has one annotated transcript and one annotated polypeptide.
Protein features are: ENTH/VHS; Src homology-3 domain; Ubiquitin interacting motif; VHS; VHS subgroup.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of moderate expression.
Peak expression observed during late larval stages, during early pupal stages.
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