Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
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Gene name RecQ5
Flybase description The gene homolog of RecQ is referred to in FlyBase by the symbol Dmel\RecQ5 (CG4879, FBgn0027375).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -15.7705 -9.766 -17.064807 -10.8024 -28.219023 -12.598 -17.06039 -20.993151
    Affimetrix absolute value 4.46 4.347 4.142 4.982 3.992 4.908 4.463 3.94
    Affymetric present call in "x" number of chips 3 2 2 3 1 3 3 1
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
There is experimental evidence that it has the molecular function: GTP binding; single-stranded DNA-dependent ATP-dependent DNA helicase activity; GTPase activity.
There is experimental evidence that it is involved in the biological process: double-strand break repair via single-strand annealing; response to DNA damage stimulus; negative regulation of mitotic cell cycle; response to X-ray; regulation of mitotic anaphase.
13 alleles are reported.
The phenotypes of these alleles are annotated with: eye; interommatidial bristle; ommatidial precursor cluster.
It has 3 annotated transcripts and 3 annotated polypeptides.
Protein features are: DEAD-like helicase; DNA helicase, ATP-dependent, RecQ type; DNA/RNA helicase, DEAD/DEAH box type, N-terminal; Helicase, C-terminal.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderate expression to a trough of very low expression.
Peak expression observed within 00-12 and 18-24 hour embryonic stages, during late larval stages, in adult female stages.
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