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Gene name | RecQ5 | ||||||||||||||||||||||||||||||||||||
Flybase description | The gene homolog of RecQ is referred to in FlyBase by the symbol Dmel\RecQ5 (CG4879, FBgn0027375). | ||||||||||||||||||||||||||||||||||||
Expression data along the gut |
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Intestinal gene expression in different physiological conditions |
Ecc15: flies orally infected with Erwinia carotovora carotovora 15. Pe: flies orally infected with Pseudomonas entomophila. Pe gacA: flies orally infecte with Pseudomonas entomophila gacA. For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe. |
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Gene details (from Flybase) | It is a protein_coding_gene from Drosophila melanogaster. There is experimental evidence that it has the molecular function: GTP binding; single-stranded DNA-dependent ATP-dependent DNA helicase activity; GTPase activity. There is experimental evidence that it is involved in the biological process: double-strand break repair via single-strand annealing; response to DNA damage stimulus; negative regulation of mitotic cell cycle; response to X-ray; regulation of mitotic anaphase. 13 alleles are reported. The phenotypes of these alleles are annotated with: eye; interommatidial bristle; ommatidial precursor cluster. It has 3 annotated transcripts and 3 annotated polypeptides. Protein features are: DEAD-like helicase; DNA helicase, ATP-dependent, RecQ type; DNA/RNA helicase, DEAD/DEAH box type, N-terminal; Helicase, C-terminal. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderate expression to a trough of very low expression. Peak expression observed within 00-12 and 18-24 hour embryonic stages, during late larval stages, in adult female stages. . |