Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
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Gene name CG10863
Flybase description This gene is referred to in FlyBase by the symbol Dmel\CG10863 (FBgn0027552).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 4.8724 10.4218 10.789967 4.4074 6.361107 7.6077 4.23425 7.336403
    Affimetrix absolute value 10.691 10.981 11.583 10.513 11.421 11.485 10.629 11.072
    Affymetric present call in "x" number of chips 3 3 3 3 3 3 3 3
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
Based on sequence similarity, it is predicted to have molecular function: alditol:NADP+ 1-oxidoreductase activity.
An electronic pipeline based on InterPro domains suggests that it is involved in the biological process: oxidation-reduction process.
6 alleles are reported.
The phenotype of these alleles is annotated with: mesothoracic tergum.
It has one annotated transcript and one annotated polypeptide.
Protein features are: Aldo/keto reductase; Aldo/keto reductase subgroup; Aldo/keto reductase, conserved site; NADP-dependent oxidoreductase domain.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of moderate expression.
Peak expression observed within 18-24 hour embryonic stages, at stages throughout the larval period, in stages of adults of both sexes.
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