Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
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Gene name VhaSFD
Flybase description The gene Vacuolar H+-ATPase SFD subunit is referred to in FlyBase by the symbol Dmel\VhaSFD (CG17332, FBgn0027779).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 3.3348 14.305 12.056109 19.4133 5.424285 6.0441 19.9521 10.544613
    Affimetrix absolute value 10.132 11.433 11.74 12.66 11.173 11.148 12.861 11.558
    Affymetric present call in "x" number of chips 3 3 3 3 3 3 3 3
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
Based on sequence similarity, it is predicted to have molecular function: hydrogen-exporting ATPase activity, phosphorylative mechanism.
There is experimental evidence that it is involved in the biological process: dsRNA transport; determination of adult lifespan.
7 alleles are reported.
The phenotype of these alleles is annotated with: Malpighian tubule.
It has 3 annotated transcripts and 3 annotated polypeptides.
Protein features are: ATPase, V1 complex, subunit H; ATPase, V1 complex, subunit H, C-terminal; Armadillo-like helical; Armadillo-type fold.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of moderately high expression.
Peak expression observed within 18-24 hour embryonic stages, at stages throughout the larval period, during late pupal stages, in stages of adults of both sexes.
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