Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
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Gene name fan
Flybase description The gene farinelli is referred to in FlyBase by the symbol Dmel\fan (CG7919, FBgn0028379).
Expression data along the gut
    Created with Highcharts 6.0.3Fold change compared to full gutRegion-specific expression of fan along the gutCropCardia/R1R2R3R4R5Hindgut-2-1012Highcharts.com
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -52.9245 -30.3332 -49.806212 -53.6155 -67.589746 -56.1585 -49.48403 -47.663001
    Affimetrix absolute value 2.694 2.739 2.552 2.661 2.689 2.752 2.942 2.708
    Affymetric present call in "x" number of chips 0 0 0 0 0 0 0 0
Intestinal gene expression in different physiological conditions
Created with Highcharts 6.0.3Fold change compared toUnchallengedFold change compared to UnchallengedExpression of fan in different experimental conditionsEcc15 4hEcc15 16hPe 4hPe 16hPe gacA 4hPe gacA 16h-2-1012Highcharts.com
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
An electronic pipeline based on InterPro domains suggests that it has the molecular function: structural molecule activity.
There is experimental evidence that it is involved in the biological process: sperm individualization.
8 alleles are reported.
The phenotype of these alleles is annotated with: cystic bulge.
It has one annotated transcript and one annotated polypeptide.
Protein features are: Major sperm protein; PapD-like; Vesicle-associated membrane protein.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of extremely low expression.
Peak expression observed in adult male stages.
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