Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
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Gene name ics
Flybase description The gene icarus is referred to in FlyBase by the symbol Dmel\ics (CG9031, FBgn0028546).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 2.0588 1.3884 -0.668158 1.531 -1.67761 1.2114 1.29081 -0.647391
    Affimetrix absolute value 9.436 8.085 7.801 8.985 8.056 8.837 8.911 7.939
    Affymetric present call in "x" number of chips 3 3 3 3 3 3 3 3
Intestinal gene expression in different physiological conditions There is not condition-dependent expression data available for this gene.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
Based on sequence similarity, it is predicted to have molecular function: small GTPase regulator activity.
There is experimental evidence that it is involved in the biological process: apposition of dorsal and ventral imaginal disc-derived wing surfaces; negative regulation of JUN kinase activity; negative regulation of JNK cascade.
3 alleles are reported.
The phenotype of these alleles is annotated with: wing blade.
It has one annotated transcript and one annotated polypeptide.
Protein features are: Leucine-rich repeat; Leucine-rich repeat, typical subtype.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of moderately high expression.
Peak expression observed at stages throughout embryogenesis, at stages throughout the larval period, at stages throughout the pupal period.
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